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Article Teaser: Q: Dear Will, I am a 62 year old male who found the bodybuilding life style about ten years ago, so I started out a little late. My testosterone has been clinical low (under 300ng/dl) for the past 3 years. I want to start hormone replacement therapy and I doctor agrees it would be a good idea for me. He wants to use standard testosterone enanthate. However, from my reading on the topic, wouldn't a less androgenic steroid like Primobolin be better?

Keep reading below...

What Do You Think Of Testosterone Replacements?

Copyright (c) 2006-2017
(See This Article in its Original Format.)

Q: Dear Will, I am a 62 year old male who found the bodybuilding life style about ten years ago, so I started out a little late. My testosterone has been clinical low (under 300ng/dl) for the past 3 years. I want to start hormone replacement therapy and I doctor agrees it would be a good idea for me. He wants to use standard testosterone enanthate. However, from my reading on the topic, wouldn't a less androgenic steroid like Primobolin be better?

Charles Linquest, Monroe WI, 53566

A: Good question Charles, and I will do my best to answer it. Though you may have started out later than some, it's never too late to derive benefit from the bodybuilding life style!

For your use, that is hormone replacement therapy (HRT), I would agree with your doctor here.

Low androgen is not by default a good thing and the androgenic aspects of testosterone have many important functions on the male body. For example, a recent study compared testosterone enanthate and methenolone enanthate (Primobolin) in men for HRT.

The study was called "Hormone replacement therapy for older men using testosterone enanthate or methenolone enanthate. (Int J Androl 2000 Jan;23(1):300-6)." As most people know, as men age, testosterone levels decline and is commonly referred to as "andropause."

This slow steady decline in testosterone levels has a negative effect on mood, sexual performance, libido, bone mass, muscle mass and the immune system. Not good! Predictably, the medical/scientific community has taken an interest in HRT for men. Some doctors worry about possible adverse effects of HRT with testosterone on the prostate, cholesterol levels, etc.

However, it's clear from the studies we have that this point that too little testosterone is just as bad for you, if not worse, than too much testosterone. The real goal of HRT with men is of course to keep testosterone in the optimal range, say the mid to high normal range found in a young healthy male. That's approximately 500-600ng/dl but it can vary depending on which lab you use.

Ok, back to the study. In this study 100mg per week of Primobolan was given via injection to 10 men aged 52-78 years old who were diagnosed as being low in testosterone (i.e. hypogonadal).

Testosterone enanthate was administered at the same dose and frequency to another group of hypogonadal men (n=9, aged 54-77 years old). Both groups got these doses for 8 weeks. The researchers looked body composition (measured by DEXA scan), mood (sense of well-being), sexual activity, libido, and check both groups prostates pre and post treatment.. They also looked at both groups testosterone levels, estradiol (estrogen) levels, and blood cholesterol levels.

Interestingly, they didn't find significant changes in body composition (muscle mass, bodyfat, etc) in either group. More important perhaps, the group receiving the Primobolan reported a significant decrease in sexual activity and libido, and an increase in prostate size at the end of the study period, with a 73% decrease in serum estradiol relative to baseline.

Four weeks after the last dose, everything went back to Normal however, showing at least the effect was reversible. Things went much better for the testosterone group, as they had an increase in sexual activity and libido with no adverse effects found on any of the tested parameters. The researchers concluded that testosterone was clearly a superior choice for HRT in men with low testosterone levels, which really should come as no surprise to people.

Of course this study does not answer all questions, was not a large study (though there are others), was low dose, and only ran 8 weeks, but it does show that testosterone is not the big bad boogie man steroid the media would like us to believe it is and clearly has therapeutic uses for men.

It's interesting that neither group had any statistically significant changes in body composition, but its what most bodybuilders already know; you need higher doses to get that effect, and you need to lift some weights! Low androgen steroids like "Primo" have their uses for sure, but for older men seeking to get the benafits of HRT, testosterone is still king in my view.


About The Author: Shop Amazon - Top Gift Ideas
Will Brink writes for numerous health, fitness, medical, and bodybuilding publications. His articles can be found in Life Extension Magazine, Muscle n Fitness, Inside Karate, Exercise For Men Only, Oxygen, Women's World, The Townsend Letter For Doctors and many more. His website is http://www.brinkzone.com

Muscle Building Nutrition
http://musclebuildingnutrition.com

A complete guide bodybuilding supplements and eating to gain lean muscle

Diet Supplements Revealed
http://aboutsupplements.com

A review of diet supplements and guide to eating for maximum fat loss

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